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Prandin (repaglinide) can be an oral diabetes medicine that helps control blood sugar levels. This medication lowers blood sugar levels by creating the pancreas to make insulin.

Prandin is utilized along with exercise and dieting to take care of diabetes type 2. Other diabetes medicines are occasionally employed in combination with repaglinide as required.

Prandin may aso be utilized for purposes unlisted within this medication guide.


Take Prandin exactly as prescribed by your doctor. Do not take in larger or smaller amounts and for longer than recommended. Follow the directions in your prescription label.

Prandin is normally taken 2 to 4 times daily, within 30 minutes before eating lunch. Follow your medical professional's instructions. If you skip meals, do not take on your dose of Prandin. Wait until the following meal.

Your blood glucose will have to be checked often, and you'll need other blood tests your doctor's office. Visit a medical expert regularly.

Know warning signs of low blood sugar levels (hypoglycemia) and the ways to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a method to obtain sugar accessible in case you might have signs and symptoms of low blood glucose. Sugar sources include orange juice, glucose gel, candy, or milk. If you've severe hypoglycemia and cannot eat or drink, readily injection of glucagon. Your doctor can provide a prescription to get a glucagon emergency injection kit and inform you the way to provide injection.

Also watch for signs and symptoms of blood glucose levels which is way too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dried-out skin, blurred vision, and weight loss.

Check your blood glucose carefully within a period of stress or illness, if you travel, exercise more than usual, drink alcohol, or skip meals. These things could affect your blood sugar and your dose needs might also change.

Your doctor might want that you stop taking Prandin to get a short time should you become ill, have a fever or infection, or if you might have surgical procedures or a medical emergency.

Ask your medical professional how to adjust your Prandin dose if required. Do not change your medication dose or schedule without a medical expert's advice.

Prandin is portion of a total program of treatment that also includes diet, exercise, and weight loss. Follow what you eat, medication, and workout routines very closely. Changing any of these factors may affect your blood glucose levels.

Use Prandin regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.


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Active ingredient: Repaglinide

Repaglinide is a white to off-white powder with molecular formula C27 H36 N2 O4 as well as a molecular weight of 452.6. PRANDIN tablets contain 0.5 mg, 1 mg, or 2 mg of repaglinide. In addition each tablet has the following inactive ingredients: calcium hydrogen phosphate (anhydrous), microcrystalline cellulose, maize starch, polacrilin potassium, povidone, glycerol (85%), magnesium stearate, meglumine, and poloxamer. The 1 mg and two mg tablets contain iron oxides (yellow and red, respectively) as coloring agents.



Side Effects

Weight gain, diarrhea, and joint may occur. If some of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your physician has prescribed medicines as he or she has judged how the help to you is greater than the risk of unwanted side effects. Many people using this medication do not have serious side effects.

Repaglinide can cause low blood glucose (hypoglycemia) especially in the event you are taking other medicines for diabetes. Consuming vast amounts of alcohol, not receiving enough calories from food, or doing unusually heavy exercise might also result in low blood sugar. Symptoms can sometimes include chills, cold sweat, dizziness, drowsiness, shaking, fast heartbeat, weakness, headache, fainting, tingling of the hands or feet, or hunger. It is often a good habit to handle glucose tablets or gel to help remedy low blood sugar levels. If you don't have these reliable forms of glucose, lift up your blood sugar quickly by consuming an instant way to obtain sugar like countertop sugar, honey, candy, or drinking a glass of juice or non-diet soda. Check with your doctor or pharmacist to determine list of positive actions in the event you miss meals.

Symptoms of high blood glucose levels (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell a medical expert immediately. Your doctor may need to adjust your diabetes medication(s).

A grave allergic attack to this particular drug is rare. However, seek immediate medical assistance should you notice any in the following signs of a serious allergic attack: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete report on possible negative effects. If you notice other effects unlisted above, contact a medical expert or pharmacist.


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Tell your doctor about all the other medications you use, especially:

cyclosporine (Gengraf, Neoral, Sandimmune);

St. John's wort;

an antibiotic like clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek);

an antifungal medication like fluconazole (Diflucan), itraconazole (Sporanox), or ketoconazole (Nizoral);

a barbiturate like phenobarbital (Solfoton);

heart or blood pressure level medication for example diltiazem (Cartia, Cardizem), nicardipine (Cardene), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), among others;

HIV/AIDS medicine for example delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), fosamprenavir (Lexiva), indinavir (Crixivan), ritonavir (Norvir), among others;

rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin); or

seizure medication for example carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin), primidone (Mysoline), while others.

You could be very likely to have hyperglycemia (high blood sugar) if you take Prandin with other drugs that raise blood sugar, such as:


diuretics (water pills);

steroids (prednisone among others);

phenothiazines (Compazine and others);

thyroid medicine (Synthroid among others);

birth control pills as well as other hormones;

seizure medicines (Dilantin yet others); and

diet pills or medicines to deal with asthma, colds or allergies.

You could be prone to have hypoglycemia (low blood sugar levels) if you take other drugs that lower blood glucose levels, such as:

probenecid (Benemid);

a blood thinner (warfarin, Coumadin);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or another salicylates (including Pepto-Bismol);

a blood thinner (warfarin, Coumadin, Jantoven, while others);

sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, yet others);

a monoamine oxidase inhibitor (MAOI); or

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos, Duetact, Actoplus Met), or rosiglitazone (Avandia, Avandaryl, Avandamet).

These lists aren't complete high are many other medicines that could increase or decrease the effects of Prandin on reducing your blood glucose. Using certain medicines will make it harder for that you tell when you have low blood sugar levels. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not begin a new medication without telling your doctor.

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Do not use Prandin should you are allergic to repaglinide, if you've got type 1 diabetes, or should you are in a state of diabetic ketoacidosis (call your physician for treatment with insulin). You should not use Prandin along with gemfibrozil (Lopid) or NPH insulin (for example isophane insulin).

Before taking repaglinide, tell your physician or pharmacist should you are allergic for it; or if you might have any other allergies. This product may contain inactive ingredients, which can cause allergies and other problems. Talk to your pharmacist for additional information. 

Before using this medication, tell your medical professional or pharmacist your history, especially of: kidney disease, liver disease.

You can experience blurred vision, dizziness, or drowsiness due to extremely low or high glucose levels. Do not drive, use machinery, or go activity that will need alertness or clear vision before you are sure it is possible to perform such activities safely.

Limit alcohol while taking medicines since it can increase the risk of developing low blood sugar.

During times during the stress, for example fever, infection, injury, or surgery, it could possibly be harder to regulate your blood sugar levels. Consult your doctor because increased stress may need a change in your treatment plan, medications, or blood glucose testing.

During pregnancy prescription drugs should be used only once clearly needed. Pregnancy might cause or worsen diabetes. Discuss a strategy with a medical expert for managing your blood glucose while pregnant. Your doctor may improve your diabetes treatment during your pregnancy. Discuss the potential risks and great things about different treatments (for example diet, exercise, and medications including insulin).

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FDA pregnancy category C. It is not known whether Prandin will harm an child. Tell your doctor if you are pregnant or prefer to conceive while using Prandin. It is not known whether repaglinide passes into breast milk or if maybe it's damaging to a nursing baby. You should not breast-feed while you consider Prandin.

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