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Precautions

Do NOT use Zocor if:

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• you've liver problems or unexplained abnormal liver function tests

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• you are pregnant or breast-feeding

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• you take a macrolide antibiotic (eg, clarithromycin, erythromycin), an HIV protease inhibitor (eg, ritonavir), itraconazole, ketoconazole, mibefradil, nefazodone, or telithromycin.

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Contact a medical expert or physician straight away if some of these connect with you.

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Some health conditions may connect to Zocor. Tell your physician or pharmacist if you have any health concerns, particularly if any in the following apply to you:

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• if you're planning to become pregnant

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• if you take any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• in case you have allergies to medicines, foods, and other substances

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• when you have low blood pressure level, kidney problems, diabetes, a serious infection, or perhaps a good reputation for seizures

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• when you have metabolism, hormonal, or electrolyte problems

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• if you are drinking alcoholic beverages or have a very good reputation for liver problems or alcohol abuse

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• for those who have recently had major surgery or a life threatening injury.

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Some medicines may communicate with Zocor. Tell your doctor if you take every other medicines, especially any in the following:

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• Amiodarone, certain azole antifungals (eg, itraconazole, ketoconazole), danazol, diltiazem, fibrates (eg, gemfibrozil, clofibrate), fluconazole, HIV protease inhibitors (eg, ritonavir), imatinib, immunosuppressants (eg, cyclosporine), macrolide antibiotics (eg, clarithromycin, erythromycin), mibefradil, nefazodone, niacin, non-nucleoside reverse transcriptase inhibitors (eg, delavirdine), risperidone, streptogramins (eg, dalfopristin), telithromycin, vasopressin receptor antagonists (eg, conivaptan), verapamil, or voriconazole simply because they may increase the risk of muscle or kidney problems

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• Bosentan, carbamazepine, rifampin, or St. John's wort since they may decrease Zocor's effectiveness

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• Anticoagulants (eg, warfarin), digoxin, macrolide immunosuppressants (eg, tacrolimus), or spironolactone because the potential risk of their unwanted side effects might be increased by Zocor.

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This is probably not a complete report on all interactions that will occur. Ask your health care provider if Zocor may interact with other medicines that you take. Check with your health care provider before you begin, stop, or customize the dose of the medicine.

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Important safety information:

• Drinking alcohol daily or perhaps considerable amounts may increase the risk of liver issues with Zocor. Check together with your doctor before drinking alcohol while you are taking Zocor.

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• Follow the dietary plan and exercise program presented to you because of your doctor.

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• Women who can be pregnant should use effective birth control while taking Zocor. Check together with your doctor for those who have queries about using birth control method.

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• Rarely, changes towards the skin, hair, and nails (eg, discoloration, dryness, hair thinning) may occur. Check along with your doctor if these effects become bothersome or cause you concern.

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• Lab tests, including blood blood choleseterol levels, liver function tests, and creatine phosphokinase (CPK) blood levels, could possibly be performed while you use Zocor. These tests may be utilized to monitor your condition or check for negative effects. Be sure to keep all doctor and lab appointments.

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• Zocor needs to be used in combination with extreme care in youngsters younger decade plus individuals who have not reached puberty; safety and effectiveness in these children haven't been confirmed.

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