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Precautions

Do not use Dapoxetine if:

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• you are allergic to the ingredient in Dapoxetine

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• you are already advised through your doctor to avoid sexual activity as a result of heart disease

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• you consider nitrates (eg, isosorbide, nitroglycerin) in any form (eg, tablet, capsule, patch, ointment), or nitroprusside

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• you use certain recreational drugs called "poppers" (eg, amyl nitrate or nitrite, butyl nitrate or nitrite).

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Contact your physician or health care provider immediately if some of these affect you.

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Some medical ailments may connect to Dapoxetine. Tell your doctor or pharmacist for those who have any health conditions, in particular when any of the following apply to you:

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• if you have allergies to medicines, foods, or other substances

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• in case you have a deformed penis (eg, Peyronie disease), blood cell problems (eg, leukemia, sickle cell anemia), or some other condition that could improve the risk of a prolonged erection (priapism)

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• for those who have a good a protracted (over 4 hours) or painful erection (priapism)

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• when you have a history of liver or kidney problems, high or low blood pressure, ulcers, bleeding problems, heart related illnesses (eg, heart failure, irregular heartbeat), or circulation system problems

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• if you have a reputation cardiac arrest, stroke, or life-threatening irregular heartbeat, especially within the past 6 months.

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Some medicines may interact with Dapoxetine. Tell your medical provider if you consider some other medicines, especially any of the following:

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• Alpha-blockers (eg, doxazosin), medicines for high blood pressure levels, nitrates (eg, isosorbide, nitroglycerin), or nitroprusside because severe low blood pressure level with dizziness, lightheadedness, and fainting may occur

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• Azole antifungals (eg, itraconazole, ketoconazole), H₂ antagonists (eg, cimetidine), HIV protease inhibitors (eg, ritonavir, saquinavir), macrolide antibiotics (eg, erythromycin), narcotic analgesics (eg, dihydrocodeine), or telithromycin because they may raise the probability of Dapoxetine's negative effects

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• Bosentan or rifampin because they may decrease Dapoxetine's effectiveness.

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This is probably not a total report on all interactions which could occur. Ask your medical provider if Dapoxetine may communicate with other medicines that you take. Check with your health care provider when you start, stop, or affect the dose of the medicine.

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Important safety information:

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• Dapoxetine could cause dizziness, drowsiness, fainting. These effects may be worse should you take it with alcohol or certain medicines. Use Dapoxetine with caution. Do not drive or perform other possible unsafe tasks and soon you know how you reply to it.

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• Dapoxetine could cause dizziness, lightheadedness, or fainting; alcohol, warm weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially inside morning. Sit or take a nap at the first sign of any of these effects.

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• Patients with heart disease taking Dapoxetine could be at increased risk for heart-related side effects, including heart attack or stroke. Symptoms of an cardiac arrest can include chest, shoulder, neck, or jaw pain; numbness of the arm or leg; severe dizziness, headache, nausea, stomach pain, or vomiting; fainting; or vision changes. Symptoms of your stroke might include confusion, vision or speech changes, one-sided weakness, or fainting. Contact your medical professional or seek medical attention immediately if you experience these symptoms.

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• Dapoxetine may rarely cause an extended (eg, over 4 hours) or painful erection. This could happen even if you are not making love. If this is just not treated straight away, it may lead to permanent sexual problems such as impotence. Contact your medical professional without delay if you have an erection that lasts greater than 4 hours.

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• Dapoxetine does not stop the spread of HIV and other sexually transmitted diseases (STDs) to others through sexual contact. Use barrier methods of contraception (eg, condoms) for those who have HIV infection or perhaps an STD.

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• Dapoxetine is not going to prevent pregnancy. If your partner can become pregnant and you also wish to prevent pregnancy, be sure to utilize an effective form of birth control method.

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• Dapoxetinemay uncommonly cause mild, temporary vision changes (eg, blurred vision, sensitivity to light, blue/green color tint to vision). Contact your medical professional if vision changes persist or are severe.

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• Do not use other medicines or control of ED while you consider Dapoxetine without first checking with your doctor.

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• Use Dapoxetine with caution within the elderly; they may be more sensitive to its effects.

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• Dapoxetine is not recommended for used in patients younger 18 years.

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