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Eldepryl is indicated as an adjunct inside management of Parkinsonian patients being treated with levodopa/carbidopa who exhibit deterioration inside quality of these reaction to this therapy.


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Take this medicine only as directed because of your doctor. Do not take a greater portion of it, don't take it more often, and don't take it for a longer time than your physician ordered.

It is the most suitable to consider this medicine before breakfast and without liquids.

If you might be with all the disintegrating tablet, ensure the hands are dry when you handle today. Do not open the blister pack that contains today until you might be ready to take it. Remove the tablet through the blister pack by peeling back the foil, then taking the tablet out. Do not push today through the foil. Do not break or split today. Place today on the top of your tongue, where it's going to melt quickly. Do not eat food or drink liquids for 5 minutes before or after investing in this medicine.

If you miss a dose of this medicine, go at the earliest opportunity. However, when it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


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The dose of the medicine changes for various patients. Follow your medical professional's orders or the directions on the label. The following information includes merely the average doses of this medicine. If your dose differs, usually do not change it out unless your medical professional informs you for this.

The quantity of medicine which you take depends about the strength from the medicine. Also, the amount of doses you take each day, time allowed between doses, and also the amount of time you take the medicine depend about the medical problem for which you're while using medicine.
For oral dosage form (tablets):
For Parkinson's disease:

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Store the medicine in the closed container at room temperature, far from heat, moisture, and direct light. Keep from freezing.
Keep out of your reach of youngsters.
Do not keep outdated medicine or medicine no more needed.

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Eldepryl can be a levorotatory acetylenic derivative of phenethylamine. It is commonly referred to inside clinical and pharmacological literature as l-deprenyl.

Side Effects

Along featuring its needed effects, medicine could potentially cause some unwanted effects. Although not these unwanted side effects may occur, whenever they do occur they may need medical help.

Check with your medical professional immediately if the following side effects occur:

More common
Chest pain (severe)
enlarged pupils
fast or slow heartbeat
headache (severe)
increase in unusual movements of the body
increased sensitivity in the eyes to light
increased sweating (possibly with fever or cold, clammy skin)
mood or any other mental changes
nausea and vomiting (severe)
stiff or sore neck

Less common or rare
Bloody or black, tarry stools
convulsions (seizures)
decreased urine
difficult or frequent urination
difficulty with breathing
difficulty with speaking
difficulty with swallowing
dizziness or lightheadedness, particularly if getting up from your lying or sitting position
dry mouth
hallucinations (seeing, hearing, or feeling things that are not there)
increased thirst
irregular heartbeat
large, flat, blue, or purplish patches in the skin
lip smacking or puckering
loss of appetite
loss of balance control
muscle pain or cramps
nausea or vomiting
numbness or tingling within the hands, feet, or lips
puffing from the cheeks
rapid or worm-like movements from the tongue
restlessness or want to keep moving
severe stomach pain
shakiness within the legs, arms, hands, or feet
shortness of breath
swelling with the feet or lower legs
swelling or inflammation from the mouth
tightness within the chest
trembling or shaking from the hands or feet
twisting movements with the body
uncontrolled chewing movements
uncontrolled movements with the face, neck, back, arms, or legs
unusual tiredness or weakness
vomiting of blood or material that looks like coffee grounds

Get emergency help immediately if any of these the signs of overdose occur:

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Symptoms of overdose
Agitation or irritability
chest pain
difficulty opening the mouth or lockjaw
dizziness (severe) or fainting
fast or irregular pulse (continuing)
high fever
high or low blood pressure
severe spasm the location where the head and heels are bent backward and also the body arched forward
troubled breathing

Some unwanted side effects may occur that always usually do not need medical help. These unwanted effects might go away during treatment since your body adjusts for the medicine. Also, your wellbeing care professional just might let you know about ways to prevent or reduce some of these unwanted side effects. Check using your health care professional if these things unwanted effects continue or are bothersome or if you've got questions about them:

More common
Abdominal or stomach pain
dizziness or feeling faint
runny nose
stuffy nose
trouble with sleeping

Less common or rare
back or leg pain
blurred or double vision
body aches or pain
burning with the lips, mouth, or throat
dryness or soreness from the throat
frequent urge to urinate
inability to move
increased sweating
irritability (temporary)
memory problems
pounding or fast heartbeat
red, raised, or itchy skin
ringing or buzzing inside the ears
slow or difficult urination
slowed movements
taste changes
uncontrolled closing from the eyelids
unusual a feeling of well-being
unusual weight loss
voice changes

Other unwanted effects unlisted may also happen in some patients. If you notice any other effects, check along with your doctor.


It is essential that your doctor look at progress at regular visits to allow for adjustments to your dose and look for any unwanted effects.

Do not take selegiline if you might have used meperidine (e.g., Demerol®) or perhaps an MAO inhibitor (MAOI) (e.g., isocarboxazid, phenelzine, tranylcypromine, Marplan®, Nardil®, or Parnate®) within the past two weeks. If you do, you could possibly develop agitation, confusion, restlessness, stomach or intestinal symptoms, sudden high temperature, elevated blood pressure, or severe convulsions.

Do not take cough medicines (e.g., dextromethorphan, Robitussin®, Pediacare®) or pain medicines (e.g., methadone, propoxyphene, tramadol, Darvon®, Dolophine®, Ultram®) while you're using this medicine. Using these medicines together could cause negative effects.

Selegiline may cause serious unwanted side effects when used in addition to some antidepressants. Tell your physician if you might have used amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac®, or Zoloft® within the past 14 days.

When selegiline is taken at doses of 10 mg or less daily for the treatment of Parkinson's disease, there aren't any restrictions on food or beverages you eat or drink. However, the risk exists that dangerous reactions, including sudden high blood pressure levels, may occur if doses above those employed for Parkinson's disease are taken with certain foods, beverages, or other medicines. These foods, beverages, and medicines include:

Also, for about 2 weeks when you stop using this medicine, simply because, beverages, and other medicines may continue to react with selegiline whether or not this was used doses more than those usually used for Parkinson's disease.

Check with your physician or hospital emergency room immediately if severe headache, stiff neck, chest pains, fast heartbeat, or nausea and vomiting occur while you're taking this medicine. These may be symptoms of a serious complication which will use a doctor's attention.

Dizziness, lightheadedness, or fainting may occur, specially when you obtain up from a lying or sitting position. Getting up slowly may help. If the problem continues or gets worse, consult your medical professional.

Selegiline might cause dryness from the mouth. For temporary relief, use sugarless candy or gum, melt pieces of ice with your mouth, or utilize a saliva substitute. However, if the mouth will continue to feel dry for longer than 14 days, check using your medical doctor or dentist. Continuing dryness of the mouth may increase the risk of dental disease, including cavities, gum disease, and fungus infections.

It is essential that your physician look at skin for melanoma (tumor) regularly if you have Parkinson's disease.

Do not stop investing in this medicine without first checking with a medical expert. Your doctor may wish one to reduce gradually the amount you are taking before stopping completely.

Hallucinations may exist in some patients. This is more common with elderly patients. If you've got hallucinations, seek advice from your medical professional.

Some those who have used this medicine had unusual changes in their behavior. Talk with your physician in case you start having problems with gambling or increased sexual libido while employing this medicine.

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