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Promethazine is a gaggle of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing what of chemicals with your brain. Promethazine also acts as a possible antihistamine. It blocks the effects of the naturally sourced chemical histamine within your body.

Promethazine can be used to deal with allergy symptoms including itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Promethazine also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as a sedative or sleep aid.

Promethazine is not to be used for treating the signs of asthma, pneumonia, or another lower respiratory tract infections.

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Take promethazine exactly as prescribed from your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on the prescription label.

Your doctor may occasionally make positive changes to dose to ensure that you receive the best results from this medication.

Promethazine could be taken with or without food or milk.

Measure liquid medicine using a marked measuring spoon or medicine cup, not which has a regular table spoon. If you tend not to possess a dose-measuring device, ask the pharmacist for starters.

Call your doctor if your symptoms do not improve, or if they deteriorate while taking promethazine.

This medication can cause that you have unusual results with certain medical tests. Tell any doctor who treats you you are using promethazine.

Seek emergency medical assistance if you think you've used an excessive amount this medicine. Overdose symptoms might include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting.


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Take becoming prescribed from your doctor.

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Store promethazine at room temperature away from moisture, heat, and light.


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Side Effects

Get emergency medical help if you might have some of these indications of a hypersensitivity: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using promethazine and call a medical expert at the same time if you might have these serious side effects:

twitching, or uncontrollable movements of one's eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking), drooling, trouble swallowing, difficulties with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling like you might distribute;

seizure (convulsions);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

hallucinations, agitation;

nausea and stomach pain, skin rash, and jaundice (yellowing from the skin or eyes);

urinating lower than usual or otherwise in any way;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color; or

slow heartrate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious promethazine side effects can sometimes include:

dizziness, drowsiness, anxiety;

blurred vision, dry mouth, stuffy nose;

ringing with your ears;

weight gain, swelling in your hands or feet;

impotence, trouble through an orgasm; or


This just isn't a complete listing of side effects among others may occur. Tell your physician about any unusual or bothersome unwanted effect.

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Stop using promethazine and call your medical professional immediately if you might have twitching or uncontrollable movements of one's eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous unwanted side effects. Promethazine can cause side effects that could impair your opinions or reactions. Be careful if you drive or do just about anything that needs you to be awake and alert. Avoid having a drink, that may increase some in the side effects of promethazine. There are many other medicines that can connect to promethazine. Tell your doctor about each of the prescription and over-the-counter medications you utilize. This includes vitamins, minerals, herbal products, and prescription drugs given by other doctors. Do not use a new medication without telling a medical expert. Keep a list together with you of every one of the medicines you utilize and show this list to any doctor or any other healthcare provider who treats you.

Important safety information:

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Promethazine should not be given to a child younger than two years old. Promethazine can cause severe breathing problems or death in a youngster younger than 2. Carefully follow your physician's instructions when giving this medicine to a youngster of any age. Do not use this medication if you've got severe asthma, emphysema, or another breathing problem, or if you are allergic to promethazine and other phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), thioridazine (Mellaril), or trifluoperazine (Stelazine).

If you've got certain conditions, you will need a dose adjustment or special tests to soundly use prescription drugs. Before you take promethazine, tell your medical professional if you might have:

a reputation seizures;

heart disease or blood pressure;

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liver or kidney disease;

severe asthma, emphysema, chronic obstructive pulmonary disease (COPD) or another breathing problem;

sleep apnea (breathing stops throughout sleep);


a stomach ulcer or digestive obstruction;

bone marrow depression;

adrenal gland tumor (pheochromocytoma);

enlarged prostate or issues with urination;

low levels of calcium within your blood (hypocalcemia); or

if you have ever had a serious side-effect with all the promethazine or any other phenothiazine.

FDA pregnancy category C. It is not known whether promethazine is harmful with an baby. Tell your doctor if you are pregnant or plan to get pregnant during treatment. It is not known whether promethazine passes into breast milk or if it could possibly harm a nursing baby. Do not use medicines without telling your doctor should you are breast-feeding a baby. Older adults may be more likely to have unwanted effects from promethazine.

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