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Precautions

 Do NOT use Colchicine if:

• you might be allergic to your ingredient in Colchicine

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• the patient is a child with gout

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• you have liver or kidney problems and you really are also taking certain other medicines (eg, atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir or any medicine which has ritonavir, saquinavir, telithromycin)

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Contact your physician or doctor straight away if these sign up for you.

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Some medical conditions may talk with Colchicine . Tell a medical expert or pharmacist in case you have any health conditions, especially if any of the following connect with you:

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• if you happen to be pregnant, planning to get pregnant, or are breast-feeding

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• if you might be taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• in case you have allergies to medicines, foods, or other substances

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• if you have a blood disorder, stomach or bowel problems, heart related illnesses, or liver or kidney problems, or if you are having dialysis

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Some medicines may connect to Colchicine . Tell your doctor if you're taking any other medicines, especially any from the following:

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• Digoxin, fibrates (eg, fenofibric acid), gemfibrozil, or HMG-Co A reductase inhibitors (eg, simvastatin) because the risk of severe or fatal muscle problems could be increased

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• Aprepitant, atazanavir, clarithromycin, cyclosporine, diltiazem, erythromycin, fluconazole, HIV protease inhibitors (eg, fosamprenavir), indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ranolazine, ritonavir or any medicine which contains ritonavir, saquinavir, telithromycin, or verapamil since they might increase the chance of Colchicine 's negative effects, including severe or fatal negative effects

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• Sympathomimetics (eg, pseudoephedrine, albuterol) for the reason that likelihood of their side effects could be increased

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This might not be a complete report on all interactions which could occur. Ask your doctor if Colchicine may connect to other medicines which you take. Check with your health care provider before you begin, stop, or change the dose from a medicine.

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Important safety information

• Do NOT take more than the recommended dose without checking with your medical professional.

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• Check with your medical professional when you use medicines that could cause drowsiness (eg, sleep aids, muscle relaxers) while you're using Colchicine ; it may improve their effects. Ask your friendly phamacist for those who have questions regarding which medicines may cause drowsiness.

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• Colchicine may lower the ability of the body to address infection. Avoid contact with people who have colds or infections. Tell your medical professional if you notice signs and symptoms of infection like fever, sore throat, rash, or chills.

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• Colchicine may lessen the quantity of clot-forming cells (platelets) with your blood. Avoid activities that may cause bruising or injury. Tell a medical expert in case you have unusual bruising or bleeding. Tell your doctor when you have dark, tarry, or bloody stools.

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• Accidental ingestion or overdose of Colchicine has been fatal in children and adults. Keep Colchicine out from the reach of children. In case of an overdose, call your doctor or poison control center without delay.

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• If nausea, vomiting, or diarrhea occurs, ask a medical expert for approaches to lessen these effects. Contact your doctor immediately in the event you experience severe or persistent diarrhea, nausea, or vomiting.

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• Tell your doctor or dentist that you just take Colchicine prior to deciding to get any medical or dental treatments, emergency care, or surgery.

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• Rarely, Colchicine may decrease fertility in men. Discuss any questions or concerns with a medical expert.

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• Colchicine may hinder certain tests, including urine tests for red blood cells or hemoglobin. Be sure your medical professional and lab personnel know you are taking Colchicine .

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• Lab tests, including complete blood cell counts, kidney function, and liver function, may be performed while you use Colchicine . These tests could possibly be used to monitor your complaint or search for negative effects. Be sure to keep all doctor and lab appointments.

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• Use Colchicine with caution inside the elderly; they could possibly be more understanding of its effects, including muscle and nerve problems.

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• Colchicine ought to be used with extreme caution in children younger 4 years; safety and effectiveness in these children have not been confirmed.

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• Pregnancy and breast-feeding: If you conceive, contact your doctor. You will need to discuss the huge benefits and risks of using Colchicine while you are pregnant. Colchicine is located in breast milk. If you happen to be or will be breast-feeding as you use Colchicine , talk with a medical expert. Discuss any possible risks for your baby.

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