INDICATIONS
Keppra is utilized to take care of partial onset seizures in adults and kids who will be no less than 30 days old.
It can also be used to deal with tonic-clonic seizures in adults and youngsters who're at least 6 years old, and myoclonic seizures in older adults and youngsters that are at the very least 12 yrs . old.
INSTRUCTIONS
Take Keppra the same manner prescribed from your doctor. Do not take in larger or smaller amounts or longer than recommended. Follow the directions on the prescription label.
Your doctor may occasionally change your dose to make sure you acquire the best results.
Keppra is often taken twice each day. Take the medicine simultaneously every day. You may take Keppra with or without food.
Measure liquid medicine which has a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not use a dose-measuring device, ask your friendly phamacist first.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill might cause excessive drug to be removed at once.
Use Keppra regularly to obtain the most benefit. Get your prescription refilled when you run out of medicine completely.
Do not stop using Keppra without first talking to your medical professional, even though you feel fine. You may have increased seizures should you stop using this medicine suddenly. You ought to use less before you stop the medication completely.
Seizures in many cases are treated having a combination of different drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions given each medication. Do not improve your doses or medication schedule without your physician's advice. .
Wear a medical alert tag or carry an ID card on the grounds that you adopt Keppra. Any health care provider who treats you have to know that you adopt seizure medication.
To make certain Keppra is just not causing harmful effects, your kidney function may need to be tested. Visit your medical professional regularly.
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If you missed a dose - consider the missed dose whenever you remember. Skip the missed dose if it is almost time for your forthcoming scheduled dose. Do not take extra medicine to generate up the missed dose.
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Important Administration Instructions
Keppra is offered orally with or without food. The Keppra dosing regimen is determined by the indication, age bracket, dosage form (tablets or oral solution), and renal function.
Prescribe the oral solution for pediatric patients with body weight ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with body weight above 20 kg.
When with all the oral solution in pediatric patients, dosing is weight-based (mg per kg) by using a calibrated measuring device (not just a household teaspoon or tablespoon).
Keppra tablets needs to be swallowed whole. Keppra tablets really should not be chewed or crushed.
Pediatric Patients
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Treatment needs to be initiated using a daily dose of 14 mg/kg into two divided doses (7 mg/kg two tmes a day). The daily dose should be increased every 14 days by increments of 14 mg/kg towards the recommended daily dose of 42 mg/kg (21 mg/kg two times a day). In the medical trial, the mean daily dose was 35 mg/kg in this generation. The effectiveness of lower doses has not been studied.
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Treatment should be initiated with a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg twice a day). The daily dose should be increased by 50 % weeks by an increment of 20 mg/kg for the recommended daily dose of 50 mg/kg (25 mg/kg two times a day). If a patient cannot tolerate a day-to-day dose of 50 mg/kg, the daily dose may be reduced. In the clinical study, the mean daily dose was 47 mg/kg with this age group.
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Treatment needs to be initiated which has a daily dose of 20 mg/kg by 50 percent divided doses (10 mg/kg twice daily). The daily dose needs to be increased every 2 weeks by increments of 20 mg/kg to the recommended daily dose of 60 mg/kg (30 mg/kg two tmes a day). If a patient cannot tolerate a daily dose of 60 mg/kg, the daily dose might be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.
For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment ought to be initiated with a daily dose of 500 mg given as two times a day dosing (250 mg two times a day). The daily dose should be increased every two weeks by increments of 500 mg to your maximum recommended daily dose of 1500 mg (750 mg two tmes a day).
For Keppra tablet dosing in pediatric patients weighing over 40 kg, treatment ought to be initiated with a daily dose of 1000 mg/day given as twice a day dosing (500 mg two times a day). The daily dose must be increased every 14 days by increments of 1000 mg/day to some maximum recommended daily dose of 3000 mg (1500 mg twice daily).
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Partial Onset Seizures
Adults 16 Years And Older
In clinical trials, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were shown to be effective. Although in a few studies there is an inclination toward greater response with higher dose [see Clinical Studies], an even boost in response with additional dose hasn't been shown.
Treatment must be initiated with a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Additional dosing increments could possibly be given (1000 mg/day additional every two weeks) to some maximum recommended daily dose of 3000 mg. Doses in excess of 3000 mg/day are already employed in open-label studies for periods of half a year and longer. There is no evidence that doses in excess of 3000 mg/day confer additional benefit.
Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment should be initiated having a dose of 1000 mg/day, given as twice-daily dosing (500 mg two tmes a day). Dosage must be increased by 1000 mg/day every 14 days to the recommended daily dose of 3000 mg. The effectiveness of doses below 3000 mg/day has not been studied.
Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment must be initiated having a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Dosage must be increased by 1000 mg/day every 2 weeks to the recommended daily dose of 3000 mg. The effectiveness of doses lower than 3000 mg/day will not be adequately studied.
Pediatric Patients Ages 6 To < 16 Years
Treatment ought to be initiated which has a daily dose of 20 mg/kg into two divided doses (10 mg/kg twice daily). The daily dose must be increased every fourteen days by increments of 20 mg/kg for the recommended daily dose of 60 mg/kg (30 mg/kg twice a day). The effectiveness of doses under 60 mg/kg/day will not be adequately studied. Patients with body mass ≤ 20 kg must be dosed with oral solution. Patients with weight above 20 kg may be dosed with either tablets or oral solution. Only whole tablets needs to be administered.
Adult Patients With Impaired Renal Function
Keppra dosing have to be individualized according for the patient's renal function status.
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STORAGE
Store Keppra at room temperature far from moisture, heat, and light-weight.
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Get emergency medical help in the event you have these warning signs of an allergic reaction to Keppra: hives; difficult breathing; swelling of one's face, lips, tongue, or throat.
Report any new or worsening symptoms to your physician, including: mood or behavior changes, depression, anxiety, or in the event you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Call your physician at the same time should you have a serious unwanted effect for example:
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Less serious Keppra negative effects may include:
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This just isn't a complete listing of side effects among others may occur. Tell your medical professional about any unusual or bothersome side effect.
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You should not use Keppra if you are allergic to levetiracetam.
To be sure you can safely take Keppra, tell your physician in the event you have kidney disease or high blood pressure levels.
You might have thoughts about suicide while investing in this medicine. Tell your doctor if you have the signs of depression or suicidal thoughts throughout the first many weeks of treatment, or as soon as your dose is changed.
Your family and other caregivers should also be aware of changes in your mood or symptoms. Your doctor will need to check you at regular visits.
FDA pregnancy category C. It is just not known whether Keppra will harm an child, but using a seizure in pregnancy could harm the mother along with the baby. Tell your doctor in the event you are pregnant or want to conceive while applying this medication. Do not start or stop taking Keppra while pregnant without your medical professional's advice. Seizure control is vital when pregnant. The benefit of preventing seizures may outweigh any risks posed by taking Keppra. Follow a medical expert's instructions about taking Keppra if you are pregnant. Levetiracetam can pass into breast milk and might harm a nursing baby. You should not breast-feed while you are using Keppra. Do not give this medication to a child devoid of the advice of your doctor. Your child's dose needs depend on age and weight. The child should remain under the care of your doctor while employing this medicine.
Do not stop using Keppra without first conversing with a medical expert, even if you feel fine. You may have increased seizures if you stop using Keppra suddenly. You ought to use much less when you stop the medication completely.
You could have thoughts about suicide while taking Keppra. Your doctor should check you at regular visits. Do not miss any scheduled appointments.
Report any new or worsening symptoms to your medical professional, for example: mood or behavior changes, depression, anxiety, or in case you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Wear a medical alert tag or carry an ID card on the grounds that you adopt Keppra. Any medical care provider who treats you have to know that you're taking seizure medication.
Keppra may impair your notions or reactions. Be careful in the event you drive or do anything whatsoever that will need you to be alert. Tell your medical professional if you are pregnant or plan to conceive while using this medication. Do not start or stop taking Keppra in pregnancy without a medical expert's advice. Having a seizure in pregnancy could harm both mother and also the baby. Seizure control is very important when pregnant and also the great things about preventing seizures may outweigh any risks posed by using Keppra.
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Avoid alcohol consumption. It can increase a number of the side effects of Keppra and could also increase the chance of seizures. This medication may impair your opinions or reactions. Be careful in case you drive or do anything that requires that you be alert.
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