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Precautions

Do NOT use Endep if:

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• you might be allergic to the ingredient in Endep
• you are taking or took a monoamine oxidase inhibitor (MAOI) (eg, phenelzine, selegiline) during the last 14 days

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• you take antihistamines (eg, diphenhydramine), cisapride, droperidol, a ketolide (eg, telithromycin) , a macrolide (eg, erythromycin), mibefradil, or pimozide
• you're recovering from a heart attack.

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Contact your physician or doctor immediately if some of these sign up for you.

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Some health conditions may communicate with Endep. Tell your medical professional or pharmacist when you have any health concerns, particularly if any in the following affect you:

• if you might be pregnant, about to conceive, or are breast-feeding

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• if you take any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or another substances

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• for those who have a history of mental illness (eg, bipolar disorder, mania, manic-depression), or consider or attempted suicide

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• if you have alcoholism or regularly consume 3 or maybe more booze per day

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• for those who have glaucoma, an irregular heartbeat, heart problems, chest pain, liver disease, prostate problems, thyroid disease, or can't urinate (urinary retention)

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• when you have a reputation seizures, epilepsy, or porphyria.

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Some medicines may connect to Endep. Tell your medical provider if you take any other medicines, especially any from the following:

• MAOIs (eg, phenelzine, selegiline) since they can cause serious, sometimes life-threatening, reactions. Do not take MAO inhibitors with, or within fourteen days of taking, Endep

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• Anticholinergics (eg, scopolamine), bupropion, cimetidine, fluconazole, phenothiazines (eg, chlorpromazine), SSRIs (eg, fluoxetine), terbinafine, or valproic acid because unwanted effects like blurred vision, difficult urination, drowsiness or sedation, dry mouth, or lightheadedness may occur

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• Antihistamines (eg, diphenhydramine), cisapride, droperidol, ketolides (eg, telithromycin), macrolides (eg, erythromycin), mibefradil, pimozide, or streptogramins (eg, quinupristin/dalfopristin) because serious side effects about the heart (eg, racing heartbeat, dizziness, fainting, life-threatening abnormal heartbeat leading to unconsciousness, and lack of heartbeat, could possibly be increased by Endep
• Carbamazepine, thyroid medicines (eg, levothyroxine), or stimulants (eg, albuterol, pseudoephedrine) because their negative effects could possibly be increased by Endep

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• Warfarin because unwanted effects like serious bleeding may be increased by Endep

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• Clonidine, guanethidine, or guanfacine since the effectiveness of the medicines could possibly be decreased.

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This will not be a whole listing of all interactions which could occur. Ask your doctor if Endep may connect to other medicines that you just take. Check with your physician before you start, stop, or affect the dose from a medicine.

Important safety information:

• Endep could cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that may be dangerous until you understand how you reply to Endep. Using Endep alone, along with other medicines, or with alcohol may lessen your skill they are driving or perform other very damaging tasks.

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• Avoid having a drink or taking other medicines that can cause drowsiness (eg, sedatives, tranquilizers) while taking Endep. Endep will add on the connection between alcohol and other depressants. Ask the pharmacist in case you have queries about which medicines are depressants.
• Endep could cause dizziness, lightheadedness, or fainting; alcohol, summer, exercise, or fever may increase these effects. To prevent them, crunch or stand slowly, specifically in the morning. Sit or lie down with the first sign of some of these effects.
• Involuntary and uncontrollable movements may develop in patients taking Endep. Occurrence is highest among the elderly, especially women. The risk of developing these involuntary movements and the likelihood they will become permanent are increased with long-term use sufficient reason for high doses. However, it's possible to develop these symptoms after short-term use at low doses. Contact your health care provider simultaneously if any of the following occur: involuntary movements with the tongue, face, mouth, or jaw (eg, protrusion of tongue, puffing of cheeks, puckering of mouth, chewing movements), sometimes accompanied by involuntary movements with the legs and arms.

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• Endep might cause sensitivity to sunlight. Avoid prolonged exposure towards the sun and other ultraviolet light (eg, tanning beds). Use sunscreens and wear protective clothing until tolerance is determined.
• Do not become overheated in warm weather or during exercise or any other activities since heatstroke may occur.

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• Diabetes patients - Endep may affect your blood glucose levels. Check blood glucose levels closely. Ask a medical expert when you alter the dose of your diabetes medicine.

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• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you will be using Endep.

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• Use caution inside the elderly; they may be more understanding of its effects, especially lightheadedness upon standing; rapid heartbeat; breathing problems; difficult urination; and constipation.

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• Pregnancy and breast-feeding: Endep has been shown to cause harm for the human fetus. If you plan on pregnancy, talk to your medical professional the benefits and perils of using Endep while pregnant. Endep is excreted inside breast milk. Do not breastfeed while taking Endep.

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