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Uses

INDICATIONS

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Imuran is employed to prevent rejection of a transplanted kidney. It is probably the group of medicines known as immunosuppressive agents. Azathioprine will lower your body's natural immunity in patients who receive transplants to stop rejection from the new kidney. It is also employed to relieve joint pain and swelling for patients with rheumatoid arthritis.

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INSTRUCTIONS

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Use this medicine the same manner directed through your doctor. Do not take a greater portion of it, or a reduced amount of it, than your physician ordered. Taking an excessive amount of may increase the chance of negative effects, and taking too little will not likely help your trouble.

This medicine is sometimes given in addition to other medicines. If you are choosing several medicines together, be sure you understand how to bring them in daytime. Ask your physician to assist you plan a way to be sure you take your medicines at the right times.

Do not stop taking this medicine without first checking with your medical professional.

Imuran sometimes causes queasiness. Taking this medicine after meals or at night may lessen stomach upset. Talk to a medical expert for those who have questions or continue to have problems with queasiness.

If you miss a dose of this medicine, get it as soon as possible. However, if it's almost time for your upcoming dose, skip the missed dose and get back to your normal dosing schedule. Do not double doses.

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DOSAGE

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The dose of this medicine changes many different patients. Follow your doctor's orders or directions around the label. The following information includes just the average doses with this medicine. If your dose is different, don't put it back unless your physician lets you know to do so.

The level of medicine which you take depends for the strength of the medicine. Also, the quantity of doses you're taking daily, the time allowed between doses, and the period of time you are taking the medicine depend for the condition that you can are using the medicine.
For oral dosage form (tablets):
For kidney transplant rejection:

For arthritis rheumatoid: 

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STORAGE 

Store the medicine in a closed container at room temperature, faraway from heat, moisture, and direct light. Keep from freezing.
Keep out from the reach of youngsters.
Do not keep outdated medicine or medicine no more needed.
Ask your doctor how you should dump any medicine you tend not to use.

Side Effects

Along using its needed effects, medicine could potentially cause some negative effects. Although not these negative effects may occur, when they do occur they might need medical attention.

Check with your doctor immediately if any in the following unwanted effects occur:


More common

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Incidence mysterious

Some negative effects may occur that usually tend not to need medical attention. These unwanted effects may go away during treatment as your body adjusts towards the medicine. Also, your health care professional might be able to tell you about ways to prevent or reduce some of these unwanted effects. Check along with your health care professional if any in the following unwanted effects continue or are bothersome or in case you have any queries about them:
More common
Nausea or vomiting (mild)
swollen joints
Incidence mysterious
Hair loss or thinning of the hair

Other side effects unlisted might also happen in some patients. If you notice every other effects, check using your doctor.

Call a medical expert for medical advice about side effects.

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Precautions

If you will end up using this medicine for years, it's very important that your doctor check you at regular visits for any problems or unwanted effects that may be brought on by this medicine. Blood tests may be needed to evaluate for negative effects.

Using this medicine when you are pregnant may damage your child. Use an effective form of contraceptive to help keep from getting pregnant. If you think you have conceive with all the this medicine, tell your doctor immediately.

Do not make use of this medicine in case you are also taking mercaptopurine (Purinethol®). Using these medicines together could cause serious unwanted effects.

If you are using azathioprine for arthritis, ensure your medical professional knows in the event you received chlorambucil (Leukeran®), cyclophosphamide (Cytoxan®, Neosar®), or melphalan (Alkeran®) to treat your arthritis in the past. Using azathioprine after these medicines may improve your risk for negative effects. Talk to your doctor when you have questions regarding this.

This medicine may enhance your likelihood of getting some types of cancer, especially from the skin, lymph system (lymphoma), or blood (leukemia). Talk to your medical professional for those who have concerns relating to this risk.

Use sunscreen or sunblock lotions with a sun protection factor (SPF) of at least 15 on a regular basis when you are outdoors. Wear protective clothing and hats, and stay beyond direct sunlight involving the hours of 10 a.m. and 3 p.m. Avoid sunlamps and tanning beds.

While you are receiving treatment with azathioprine, and once you stop treatment from it, usually do not have any immunizations (vaccines) without your doctor's approval. Azathioprine may lessen your body's resistance along with the vaccine might not exactly act as well or you might have the infection the vaccine is meant to prevent. In addition, you should not be around other persons residing in your family who receive live virus vaccines because there is a possibility they might pass herpes on you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not get near to them and usually do not stay inside same room with these for too long. If you might have questions about this, talk to a medical expert.

Azathioprine can temporarily lower the amount of white blood cells within your blood, improving the chance of getting disease. It can also lower the amount of platelets, which are needed for proper blood clotting. If this occurs, a number of precautions you'll be able to take, specially when your blood count is low, to relieve the probability of infection or bleeding:

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Check with your doctor without delay when you have more than one of such symptoms while you are utilizing this medicine: severe nausea / vomiting; diarrhea; fever; rash; an overall a feeling of discomfort or illness; muscle or joint; lightheadedness or dizziness; or unusual tiredness or weakness. These could be symptoms of the serious reaction on the medicine inside your bowel (intestine).

Do not take other medicines unless they've been discussed with your physician. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or nutritional vitamin supplements.

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