INDICATIONSLevodopa is transformed into a chemical called dopamine (DOE pa meen) within the brain. Symptoms of Parkinson's disease could be a result of 'abnormal' amounts of dopamine within the brain.
Carbidopa aids in preventing the breakdown of levodopa before it can attain the brain and work.
The mixture of carbidopa and levodopa is employed to treat Parkinson symptoms like muscle stiffness, tremors, spasms, and poor muscle control. This medication can be used to deal with Parkinson symptoms brought on by co poisoning or manganese intoxication.
Carbidopa and levodopa could also be used for other purposes not listed within this medication guide.
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If you might be already taking levodopa (Larodopa, Dopar), you must stop taking it at least 12 hours before starting taking carbidopa and levodopa.
Take exactly as prescribed through your doctor. Do not take in larger or smaller amounts and more than recommended. Follow the directions in your prescription label.
Carbidopa and levodopa might be taken with or without food. Take your doses at regular intervals to keep a reliable quantity of the drug in your body all the time.
Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. Breaking or opening the pill could cause a lot of drug to be released in the past.
The regular tablet may be broken or crushed as required to make it easier to swallow.
To consider the orally disintegrating tablet (Parcopa):
Keep named rolling around in its blister pack until you're ready to consider the medicine. Open the package and peel back the foil from these days blister. Do not push a tablet through the foil otherwise you damages named.
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Using dry hands, remove the tablet and set it within your mouth. It will start to dissolve straight away.
Do not swallow the tablet whole. Allow it to dissolve inside your mouth without chewing. Swallow repeatedly as these days dissolves.
It may take around weeks of employing carbidopa and levodopa before your symptoms improve. For best results, keep while using medication as directed. Talk with your doctor if the symptoms tend not to improve after a couple of weeks of treatment. Also educate doctor if your outcomes of medicines appear to wear off quickly involving doses.
To make sure this prescription medication is helping your complaint and is not causing harmful effects, your blood should be tested often. Your heart, liver, and kidney function can also have to be tested. Visit a medical expert regularly.
This medication may cause unusual results with certain lab tests. Tell any doctor who treats you that you're using carbidopa and levodopa.
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Store at room temperature faraway from moisture, heat, and light-weight.
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You may realize that your sweat, urine, or saliva appears dark in color, for example red, brown, or black. This is not a harmful side effect, nonetheless it could cause staining of your respective clothes or bedsheets.
Get emergency medical help in case you have all of these warning signs of a hypersensitivity: hives; difficulty breathing; swelling of one's face, lips, tongue, or throat. Call a medical expert simultaneously when you have any of these serious unwanted effects:
restless muscle movements within your eyes, tongue, jaw, or neck;
worsening of tremors (uncontrolled shaking);
high fever, stiff muscles, sweating, fast or uneven heartbeats, rapid breathing, feeling just like you might distribute;
painful or difficult urination;
severe nausea, vomiting, or diarrhea;
uneven pulse rate or fluttering inside your chest;
confusion, hallucinations, anxiety, agitation, depressed mood, thoughts of suicide or hurting yourself;
chest pain or heavy feeling, pain spreading for the arm or shoulder.
Less serious unwanted side effects can include:
mild nausea, dry mouth, loss in appetite, heartburn, diarrhea, constipation;
headache, dizziness, drowsiness, blurred vision;
sneezing, stuffy nose, cough, or any other cold symptoms;
sleep problems (insomnia), strange dreams;
muscle pain, numbness or tingly feeling; or
skin rash or itching.
This is not a complete list of unwanted effects while others may occur. Call your doctor for medical health advice about negative effects.
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Do not take carbidopa and levodopa if you have used an MAO inhibitor including isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening unwanted side effects may appear with carbidopa and levodopa prior to the MAO inhibitor has cleared from the body.
You ought not take medicines if you might be allergic to carbidopa (Lodosyn) or levodopa (Larodopa), or when you have:
unusual skin lesions that have not been checked by way of a doctor; or
a history of malignant melanoma (skin cancer).
If you have some of these other conditions, you may need a dose adjustment or special tests:
heart disease, blood pressure, coronary artery disease, a heart rhythm disorder, or perhaps a prior heart attack;
asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder;
liver or kidney disease;
an endocrine (hormonal) disease;
a stomach or intestinal ulcer;
wide-angle glaucoma; or
depression or other mental illness.
Carbidopa and levodopa may cause you to get to sleep during normal daytime activities for example working, talking, eating, or driving. You may fall asleep suddenly, even with feeling alert. Tell your medical professional if you have any difficulty with daytime sleepiness or drowsiness.
You may have increased sexual urges, unusual urges to gamble, or any other intense urges while taking carbidopa and levodopa. It is not known if the medicine actually causes this effect. Talk with your doctor if you feel you've any intense or unusual urges while taking carbidopa and levodopa.
Some people taking medicines for Parkinson's disease are suffering from melanoma (melanoma). However, people who have Parkinson's disease could possibly have a higher risk than most people for developing melanoma. Talk to your physician about your specific risk and what skin symptoms to view for. You may need to have regular skin exams.
FDA pregnancy category C. It is not known whether carbidopa and levodopa will harm an child. Tell your physician if you might be pregnant or want to become pregnant while using the this medication. Carbidopa and levodopa may pass into breast milk and may harm a nursing baby. Do not use prescription drugs without telling a medical expert if you're breast-feeding a child.
The disintegrating tablet (such as Parcopa) might have phenylalanine. Talk to your medical professional before by using this form of carbidopa and levodopa if you have phenylketonuria (PKU).
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If you missed the dose take it once you remember. Skip the missed dose if it's almost time for your upcoming scheduled dose. Do not take extra medicine to generate inside the missed dose.
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